MCA Winner

ACTIVFOLATE

  • A Body-Ready, Fourth Generation Patented Folate
  • Proprietary Soluble Fiber Increases Stability
  • Vegetarian, Micro Capsule Size
  • Third Party Laboratory Tested
  • No Preservatives, Artificial Additives

Ingredients

Supplement Facts

  • Serving Size : 1 Capsule

    Servings Per Container : 60

  •  

    Amount Per Serving % DV

  • Folate (as Quatrefolic
    (6s)-5-Methyltetrahydrofolic
    Acid Glucosamine Salt : 740 mcg)

    400 mcg   100 %

Other Ingredients: Isomaltodextrin, Citric Acid, Hydroxycellulose Methylcellulose, Water.

Supplement Facts

  • Serving Size : 1 Capsule

    Servings Per Container : 30

  •  

    Amount Per Serving % DV

  • Folate (as Quatrefolic
    (6s)-5-Methyltetrahydrofolic
    Acid Glucosamine Salt : 740 mcg)

    400 mcg   100 %

Other Ingredients: Isomaltodextrin, Citric Acid, Hydroxycellulose Methylcellulose, Water.

Suggested use

One capsule daily, or as directed by your healthcare professional.

Keep out of the reach of children. Keep tightly closed in a cool, dry place. If taking other nutritional supplements or medication, consult your healthcare practitioner before use.

  • Folate is...

    Folate is a generic name for a naturally occurring family of B-group vitamins. Folates are widely distributed in nature and are essential for the maintenance of body health. As humans (and other mammals) cannot synthesize folates, they must be obtained via diet.

     

     

  • The generations of Folate...

    However, natural folates (the first generation) are susceptible to oxidation, they rapidly lose activity in foods and have a bioavailability range of 25-50%, depending on kind of food.

    On the contrary, folic acid, the synthetic form of Monoglutamyl Folate, is almost completely stable for months or even years and can be considered as a “second generation of folate, the stable one”. 5-Methyltetrahydrofolate Calcium Salt is the third generation, it was the only folic acid derivative available on the market, and able to penetrate the body cells without further metabolism.

    ACTIVFOLATE uses Quatrefolic, the fourth generation folate derivatives, a new generation of folate derivative made up of (6S)-5-Methyltetrahydrofolate Glucosamine Salt which is able to overcome the existing calcium salt form limitations related to stability, poor solubility and bioavailability.

    generations of folate

    • 1st generation

      Form : FOOD FOLATE

      Features : Existing in food and fruits. Susceptible to oxidation, rapidly lose activity.

    • 2nd generation

      Form : FOLIC ACID

      Features : Synthetic, does not occur in nature but can be utilized by the human body as a precursor. However, need to be converted to active 5-MTHF with key enzyme.

    • 3rd generation

      Form : (6S)-5-METHYLTETRAHYDROFOLATE CALCIUM SALT

      Features : Until now, 5-Methyltetrahydrofolate Calcium Salt was the only folic acid derivative available on the market, and able to penetrate the body cells without the need of further metabolism process.

    • 4th generation

      From : (6S)-5-METHYLTETRAHYDROFOLATE GLUCOSAMINE SALT

      Features : Innovative folate salt form endowed with long lasting stability as well as a peculiarly high water solubility, improved bioavailability and well established safety.

  • Advantages of activfolate...

    ACTIVFOLATE demonstrates a surprisingly high solubility in water – greater than 1 g/ml – compared with the slight solubility of the reference compound, (6S)-5-Methyltetrahydrofolate Calcium Salt (1.1 g/100 ml). ACTIVFOLATE is about 100 times more soluble than the calcium salt. The patented folate used in ACTIVFOLATE has been shown in preclinical and clinical studies to have a higher bioavailability than calcium salt derivatives. ACTIVFOLATE also chooses patented soluble fiber from Japan to increase stability of folate. Small size capsule makes it easier for Asian and pregnant women to swallow.

    Other folate supplement vs activfolate

    Other folate supplement

    Activfolate

    Form
    Folic acid
    (6S)-5-MTHF
    Natural exist
    No
    Yes
    Bioavailability
    Low

    Need to be converted, 33% – 51% of Asian might lack key enzyme for conversion

    High, Body-ready
    Solubility
    Low
    High

    100 times more soluble than calcium salt

    Stability
    Normal
    High
    RealPromise_ActivFolate_Capsule

    1 Capsule
    activfolate
    =

    • x 5 PLATES BROCCOLI
    • x 44 CUPS YOGURT
    • x 16 EGGS
  • Folic acid supplement during pregnancy...

    Every ACTIVFOLATE capsule contains 400 mcg of patent (6S)-5- Methyltetrahydrofolate Glucosamine Salt. It meets the suggested daily dose for pregnant woman from American Pregnancy Association (APA). It’s common knowledge that folic acid is one of the most important B vitamins to take during pregnancy. APA suggests consuming 400 – 800 mcg of folate everyday throughout entire pregnancy. If you’re trying to conceive, it’s also recommended that you consume this same amount of folic acid (400 mcg for pre-pregnancy is generally fine) to maximize your chances of getting pregnant.

    • 3 months before getting pregnant

    • 3 months into pregnancy

    • late pregnancy

    Three months before and after pregnancy is the critical period for folic acid supplementation, and then continue to be added until the end of pregnancy.

    PREGNANCY STAGES

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Where to Buy

Practitioner exclusive

Where to Buy

Purchase online

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